Gene name:
Fcer1a (Fce1a) ;
Protein name:
High affinity immunoglobulin epsilon receptor subunit alpha ;
Alternative:
IgE Fc receptor subunit alpha ;Fc-epsilon RI-alpha (FcERI) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains.
Function:
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Subcellular Location:
Isoform 2
Secreted
Protein Attributes:
50:
MDTGGSARLC | LALVLISLGV | MLTATQKSVV | SLDPPWIRIL | TGDKVTLICN |
100:
GNNSSQMNST | KWIHNDSISN | VKSSHWVIVS | ATIQDSGKYI | CQKQGFYKSK |
150:
PVYLNVMQEW | LLLQSSADVV | LDNGSFDIRC | RSWKKWKVHK | VIYYKDDIAF |
200:
KYSYDSNNIS | IRKATFNDSG | SYHCTGYLNK | VECKSDKFSI | AVVKDYTIEY |
245:
RWLQLIFPSL | AVILFAVDTG | LWFSTHKQFE | SILKIQKTGK | GKKKG
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat High affinity immunoglobulin epsilon receptor subunit alpha
ELISA Kit for Rat High affinity immunoglobulin epsilon receptor subunit alpha
ELISA Kit for Rat High affinity immunoglobulin epsilon receptor subunit alpha
CLIA Kit for Rat High affinity immunoglobulin epsilon receptor subunit alpha
CLIA Kit for Rat High affinity immunoglobulin epsilon receptor subunit alpha
CLIA Kit for Rat High affinity immunoglobulin epsilon receptor subunit alpha
Polyclonal Antibody for Rat High affinity immunoglobulin epsilon receptor subunit alpha
Polyclonal Antibody for Rat High affinity immunoglobulin epsilon receptor subunit alpha
Polyclonal Antibody for Rat High affinity immunoglobulin epsilon receptor subunit alpha
Monoclonal Antibody for Rat High affinity immunoglobulin epsilon receptor subunit alpha
Monoclonal Antibody for Rat High affinity immunoglobulin epsilon receptor subunit alpha
Monoclonal Antibody for Rat High affinity immunoglobulin epsilon receptor subunit alpha
Protein for Rat High affinity immunoglobulin epsilon receptor subunit alpha
Protein for Rat High affinity immunoglobulin epsilon receptor subunit alpha
Protein for Rat High affinity immunoglobulin epsilon receptor subunit alpha
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.
Kochan J.
Submitted (1988-03) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Mast cell .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-16;ALTERNATIVE SPLICING
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;INDUCTION
7.
"Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling."
Bailey M.J.
,
Coon S.L.
,
Carter D.A.
,
Humphries A.
,
Kim J.S.
,
Shi Q.
,
Gaildrat P.
,
Morin F.
,
Ganguly S.
,
Hogenesch J.B.
,
Weller J.L.
,
Rath M.F.
,
Moller M.
,
Baler R.
,
Sugden D.
,
Rangel Z.G.
,
Munson P.J.
,
Klein D.C.
J. Biol. Chem.284:7606-7622(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;INDUCTION